منابع مشابه
IUPAC Systematic Name: 4′-Hydroxyacetanilide Synonyms: 4-Acetamidophenol; acetaminophen; 4-acetaminophenol; 4-(acetylamino)- phenol; 4-(N-acetylamino)phenol; 4-hydroxyacetanilide; 4′-hydroxyacetanilide; N-(4- hydroxyphenyl)acetamide
1.1 Chemical and physical data 1.1.1 Nomenclature Chem. Abstr. Serv. Reg. No.: 103-90-2 Deleted CAS Reg. No.: 8055-08-1 Chem. Abstr. Name: N-(4-Hydroxyphenyl)acetamide IUPAC Systematic Name: 4′-Hydroxyacetanilide Synonyms: 4-Acetamidophenol; acetaminophen; 4-acetaminophenol; 4-(acetylamino)phenol; 4-(N-acetylamino)phenol; 4-hydroxyacetanilide; 4′-hydroxyacetanilide; N-(4hydroxyphenyl)acetamide
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BACKGROUND The retinoid 4-oxo-N-(4-hydroxyphenyl)retinamide (4-oxo-4-HPR) is a polar metabolite of fenretinide (4-HPR) very effective in killing cancer cells of different histotypes, able to inhibit 4-HPR-resistant cell growth and to act synergistically in combination with the parent drug. Unlike 4-HPR and other retinoids, 4-oxo-4-HPR inhibits tubulin polymerization, leading to multipolar spind...
متن کاملc-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide.
N-(4-Hydroxyphenyl)retinamide (4-HPR), a retinoic acid analog, induces apoptosis in several cell types. The mechanism by which 4-HPR initiates apoptosis remains poorly understood. We examined the effects of 4-HPR on two prostate carcinoma cell lines, LNCaP (an androgen-sensitive, p53(+/+) cell line) and PC-3 (an androgen-insensitive, p53(-/-) cell line). 4-HPR caused sustained c-Jun N-terminal ...
متن کامل4-Ethoxy-N-(4-ethoxyphenyl)-N-(4-nitrophenyl)aniline
In the title mol-ecule, C22H22N2O4, the eth-oxy-phenyl rings are oriented at dihedral angles of 69.31 (13) and 75.90 (13)° to the nitro-phenyl ring and are twisted to each other, making a dihedral angle of 78.55 (13)°. In the crystal, weak C-H⋯O hydrogen bonds and C-H⋯π inter-action link the mol-ecules into a three-dimensional supra-molecular architecture.
متن کاملN 4,N 4′-Bis(4-methoxybenzylidene)-3,3′-dimethylbenzidine
The mol-ecule of the title compund, C(30)H(28)N(2)O(2), a Schiff base synthesised via a condensation reaction between 4-meth-oxy-benzaldehyde and 3,3'-dimethyl-benzidine, a crystallographic twofold rotation axis passes through the mid-point of the C-C bond of the biphenyl unit. Thus, the asymmetric unit comprises one half-mol-ecule. In the biphenyl unit, the aromatic rings are twisted by 13.49 ...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2013
ISSN: 1600-5368
DOI: 10.1107/s1600536813006132